- Posts: 15593
- Thank you received: 163
Please Log in or Create an account to join the conversation.
Please Log in or Create an account to join the conversation.
Summary
What is already known about this topic?
Previous infection with SARS-CoV-2 or COVID-19 vaccination can provide immunity and protection against subsequent SARS-CoV-2 infection and illness.
What is added by this report?
Among COVID-19–like illness hospitalizations among adults aged ≥18 years whose previous infection or vaccination occurred 90–179 days earlier, the adjusted odds of laboratory-confirmed COVID-19 among unvaccinated adults with previous SARS-CoV-2 infection were 5.49-fold higher than the odds among fully vaccinated recipients of an mRNA COVID-19 vaccine who had no previous documented infection (95% confidence interval = 2.75–10.99).
What are the implications for public health practice?
All eligible persons should be vaccinated against COVID-19 as soon as possible, including unvaccinated persons previously infected with SARS-CoV-2.
Previous infection with SARS-CoV-2 (the virus that causes COVID-19) or COVID-19 vaccination can provide immunity and protection from subsequent SARS-CoV-2 infection and illness. CDC used data from the VISION Network* to examine hospitalizations in adults with COVID-19–like illness and compared the odds of receiving a positive SARS-CoV-2 test result, and thus having laboratory-confirmed COVID-19, between unvaccinated patients with a previous SARS-CoV-2 infection occurring 90–179 days before COVID-19–like illness hospitalization, and patients who were fully vaccinated with an mRNA COVID-19 vaccine 90–179 days before hospitalization with no previous documented SARS-CoV-2 infection. Hospitalized adults aged ≥18 years with COVID-19–like illness were included if they had received testing at least twice: once associated with a COVID-19–like illness hospitalization during January–September 2021 and at least once earlier (since February 1, 2020, and ≥14 days before that hospitalization). Among COVID-19–like illness hospitalizations in persons whose previous infection or vaccination occurred 90–179 days earlier, the odds of laboratory-confirmed COVID-19 (adjusted for sociodemographic and health characteristics) among unvaccinated, previously infected adults were higher than the odds among fully vaccinated recipients of an mRNA COVID-19 vaccine with no previous documented infection (adjusted odds ratio [aOR] = 5.49; 95% confidence interval [CI] = 2.75–10.99). These findings suggest that among hospitalized adults with COVID-19–like illness whose previous infection or vaccination occurred 90–179 days earlier, vaccine-induced immunity was more protective than infection-induced immunity against laboratory-confirmed COVID-19. All eligible persons should be vaccinated against COVID-19 as soon as possible, including unvaccinated persons previously infected with SARS-CoV-2.
Please Log in or Create an account to join the conversation.
Please Log in or Create an account to join the conversation.
Please Log in or Create an account to join the conversation.
Please Log in or Create an account to join the conversation.
Please Log in or Create an account to join the conversation.
Answer: Every one of them. Regardless of whether you've gotten the virus, recovered and been re-infected, or been vaccinated and get the virus, you are infectious. The difference is that you are far less likely to get the virus if you've been vaccinated, and thus less likely to spread it to others, and far less likely to suffer severe symptoms requiring hospitalization if you've been vaccinated.1. How many people with natural immunity are spreading the virus vs people who have only gotten the vaccine?
Impossible to know because most people who get re-infected don't go to the hospital (so their case is documented) and some of those are likely asymptomatic so unless they do weekly tests on themselves, they wouldn't even know they are re-infected.2. How many of the 140 million people who have natural immunity have gotten a re-infection compared to people who have gotten the shot and do not have natural immunity?
Please Log in or Create an account to join the conversation.
Please Log in or Create an account to join the conversation.
Those who are unvaccinated comprise about 80% of infections. At UCHealth hospitals, that ratio holds: 78% of those hospitalized and 91% of those in ICUs are unvaccinated. The ones hospitalized despite being vaccinated are often immunocompromised or significantly older.
Please Log in or Create an account to join the conversation.