Wuhan Virus Update

29 Mar 2020 09:28 #61 by ramage
Replied by ramage on topic Wuhan Virus Update
Sciencing.com has an article entitled
How do vaccines work with immune system.
Below is a section of the article that should answer your question.

How Vaccines Work
Inside the bloodstream, antigen-presenting cells, the soldiers on guard-watch, float around as they look for invaders. Once a vaccine enters the body, the APCs capture it, ingest it, tear it up and wear a piece of the antigen on their outer surfaces.

These cells head back to headquarters where immune cells cluster, like inside the lymph nodes, to share the news about the disease. Certain naïve T- and B-cells, cells not previously exposed to the disease, recognize the invader as foreign and immediately sound the alarm to rouse the troops.

After the cells activate, some of the naïve B-cells develop into plasma B-cells. T-cells start producing Y-shaped proteins – antibodies – that the immune system releases each second. Each of these antibodies tightly attaches to the targeted antigen, much like a key enters a lock, to keep the disease from entering the cells of the body.

The body’s immunity army now recognizes these antigens as the enemy and targets them for destruction. In vaccines with weakened versions of the disease, the antigens pass into the cells where special-op forces, the killer T-cells, immediately eliminate them. From that moment on, B-cells, T-helper and T-killer cells commit the disease to memory, which allows them to recognize and destroy the real disease should it enter the body in the future.

A vaccine essentially allows the body’s immunity army to practice on the pathogen, making the body stronger and helping it respond faster than it normally would if it were first encountering the disease. Researchers and scientists call this the “secondary response” to the pathogen, which results in the creation of more antibodies and memory cells to help identify the enemy in the future.

Someone who has the virus, or an attenuated virus, in their bloodstream is developing antibodies to the virus in order to remove it from the body. An example, the first smallpox "vaccine" was developed from cowpox, much less deadly, which has a genome that is very similar to smallpox. it is thought that the antibodies to cowpox also recognized smallpox. Having a different genome sequence the flu vaccine is not effective against a corona virus.

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29 Mar 2020 10:01 #62 by homeagain
Replied by homeagain on topic Wuhan Virus Update

homeagain wrote:

ramage wrote: Hopefully, the pdf attached file will open. It is information on the Features of and Combatting
a virus. It is from the Dept. of Infectious Diseases at the Johns Hopkins University.



Perhaps I am not understanding the roll of antibodies.....( VERY familiar with the value in thyroid
tests) this article APPEARS to indicate the virus has antibodies?

abcnews.go.com/Health/antibody-testing-c...rd/story?id=69856623


In general I understand the Hopkins article, I guess I am asking WHY there is not a universal
effort to duplicate the above test coming out of Telluride.

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29 Mar 2020 14:26 #63 by ScienceChic
Replied by ScienceChic on topic Wuhan Virus Update

ramage wrote: "Dr. Anthony Fauci, the health specialist on the coronavirus task force, has said the virus’s mortality rate is closer to that of a bad case of the flu. In a Thursday report published by the New England Journal of Medicine, Fauci conceded COVID-19’s death rate was twice that of the common flu, making it roughly 0.28 percent.

That rate is exceptionally low, especially when compared to that of the SARS and MERS epidemics, which peaked at 9 percent and 36 percent respectively.

His latest comments marked a major about-face for Fauci, who previously claimed the coronavirus was 10 times as deadly as the flu."

oann.com 3/27/20
Also:
Covid-19 — Navigating the Unchartered
Anthony S. Fauci, M.D., H. Clifford Lane, M.D., and Robert R. Redfield, M.D. NEJM 3/26/20

That article may have just been published in NEJM, but it was written and submitted a month ago.

Today, Dr. Fauci told Jake Tapper that we could see 100,000-200,000 deaths and millions of infected people. Much worse than this season's flu.


2019-2020 U.S. Flu Season: Preliminary Burden Estimates

"Now, more than ever, the illusions of division threaten our very existence. We all know the truth: more connects us than separates us. But in times of crisis the wise build bridges, while the foolish build barriers. We must find a way to look after one another as if we were one single tribe.” -King T'Challa, Black Panther

The truth is incontrovertible. Malice may attack it. ignorance may deride it, but in the end, there it is. ~Winston Churchill
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29 Mar 2020 15:07 #64 by ramage
Replied by ramage on topic Wuhan Virus Update
A death rate of 0.28% = 280 deaths/100,000. 2800 deaths/1 million, 196,000 deaths/70 million
cnbc.com 3/26/20
Dr. Brian Monahan, the attending physician of Congress and the U.S. Supreme Court, said he expects 70 million to 150 million people in the U.S. will become infected with COVID-19, NBC News reported Wednesday.

Above would mean 200,000 deaths/70 million =.28% This is using the higher # of deaths and the most conservative estimate of infections.

Fauci is stating the death rate 0.28% in terms of the # of deaths. The same point is being made in either instance. You have to decide what sounds more frightening to you 200,000 deaths or a death rate of 0.28% If 150 million are infected the death rate drops to approximately 0.14%.

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29 Mar 2020 15:13 #65 by ramage
Replied by ramage on topic Wuhan Virus Update
HA
"In general I understand the Hopkins article, I guess I am asking WHY there is not a universal
effort to duplicate the above test coming out of Telluride."
My only information on what is happening in Telluride is from the lay press. I would like to think that all possibilities are being considered by the CDC/NIH.

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29 Mar 2020 21:35 #66 by Blazer Bob
Replied by Blazer Bob on topic Wuhan Virus Update

FDA issues emergency authorization of anti-malaria drug for coronavirus care


www.politico.com/news/2020/03/29/fda-eme...-malaria-drug-155095

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02 Apr 2020 08:38 #67 by ramage
Replied by ramage on topic Wuhan Virus Update
‘Battlefield Medicine’: NY, NJ Doctors and Patients See Anecdotal Evidence of Hydroxychloroquine Benefits in Fighting Coronavirus

Very informative article as to what M.D.s in the New York are prescribing for their patients and the results thus far.
One of the regimens:
“This is battlefield medicine and the use of real time frontline assessment,” said Dr. Vladimir Zelenko, who practices family medicine with mostly ultra-Orthodox Jewish patients near the Orange County, New York, village of Kiryas Joel. The tightknit community has seen a deluge of coronavirus cases in recent weeks.

Zelenko has been prescribing a treatment plan of 200mg of hydroxychloroquine twice a day for 5 days, Azithromycin 500mg antibiotics once a day for 5 days, and 220mg of Zinc sulfate once a day for 5 days.
breitbart.com 4/1/20 Aaron Klein

SC hold your nose and open the article. No politics.

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02 Apr 2020 14:50 #68 by Pony Soldier
Replied by Pony Soldier on topic Wuhan Virus Update
Well, our government in all their wisdom mandated that all elective and non-critical surgery be postponed to make room for Coronavirus patients. The thing they don’t realize is that hospitals are businesses and when you take away a major source of their revenue, they have to cut costs. Hospitals here in South Carolina are furloughing workers thus reducing capacity ahead of the CV peak.

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02 Apr 2020 16:34 #69 by ramage
Replied by ramage on topic Wuhan Virus Update
Pony Solider,
Right on the money, there are O.R.'s sitting vacant, patients have had their elective
postponed. There are no cases of Covid-19 that require surgery. The term elective does not mean that the surgery is not necessary, rather it is not life threatening if not done ASAP. In the interim office staffs of these surgeons, in large part have been let go.
My advice, stock up on the NSAID of your choice because you are not going to get your knee, hip, shoulder operated on for 4-6 months , once the surgical centers, hospital are allowed to commence elective surgery.

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02 Apr 2020 20:17 #70 by Pony Soldier
Replied by Pony Soldier on topic Wuhan Virus Update
Today's new cases chart from the CDC. It looks like the curve is flattening, but that is deceptive when superimposed with the number of tests being conducted.
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